Frailty Status Modifies the Efficacy of Exercise Training Among Patients With Chronic Heart Failure and Reduced Ejection Fraction: An Analysis From the HF-ACTION Trial.
Ambarish PandeyMatthew W SegarSumitabh SinghGordon R ReevesChristopher O'ConnorIliana L PiñaDavid WhellanWilliam E KrausRobert J MentzDalane W KitzmanPublished in: Circulation (2022)
Among patients with chronic stable HFrEF, baseline frailty modified the treatment effect of aerobic ET with a greater reduction in the risk of all-cause hospitalization but not mortality.