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A comparison of rates and severity of chronic kidney disease in deceased-donor and living-donor liver transplant recipients: times matter

Yücel YankolEmily BugeaudTiffany J ZensMichael RizzariNesimi MecitGlen E LeversonDavid P FoleyJoshua D MezrichTuran KanmazOya Münevver AndaçoğluAnthony M D'AlessandroKoray Sadık AcarlıMünci KalayoğluLuis A Fernandez
Published in: Turkish journal of medical sciences (2021)
It can be concluded that LDLT provides excellent graft and patient survival, significantly reducing the overall incidence of clinically significant CKD stage progression when compared to DDLT. Moreover, there is a significantly higher incidence of CKD stage regression in LDLT compared to DDLT. These observations were maintained in both high and low model for end-stage liver disease(MELD)populations. This observation likely reflects earlier access to transplantation in LDLT as one of the contributing factors to preventing CKD progression.
Keyphrases
  • chronic kidney disease
  • end stage renal disease
  • risk factors
  • stem cells
  • cell therapy
  • free survival
  • mesenchymal stem cells
  • genetic diversity