Reproductive Factors and Colorectal Cancer Risk: A Population-Based Case-Control Study.
Efrat L AmitayTobias NiedermaierElizabeth AlwersJenny Chang-ClaudeMichael HoffmeisterHermann BrennerPublished in: JNCI cancer spectrum (2022)
Several reproductive factors were associated with lower CRC risk in women, including number of pregnancies, breastfeeding duration, and use of OC and HRT. This suggests that women's exposure to female reproductive hormones plays a key role in the difference in CRC risk between women and men and in site-specific CRC risk.