Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosis.

Caspar B SeitzFalk SteffenMuthuraman MuthuramanTimo UphausJulia KrämerSven G MeuthPhilipp AlbrechtSergiu GroppaFrauke ZippStefan BittnerVinzenz Fleischer

Published in: Therapeutic advances in neurological disorders (2021)

In summary, sNfL levels were a good predictor of future outer retinal thinning in MS. Changes within the neurofilament-rich OPL could be considered as an additional retinal marker linked to MS neurodegeneration.

Keyphrases

multiple sclerosis
optical coherence tomography
diabetic retinopathy
mass spectrometry
optic nerve
cerebrospinal fluid
ms ms
white matter