Prevalence of functional esophageal disorders and associated clinical characteristics in patients with proton-pump-inhibitor-unresponsive reflux symptoms.

Ming-Han WeiChien-Chuan ChenHui-Chuan LeeYi-Chia LeeHsiu-Po WangMing-Shiang WuJia-Feng Wu Ping-Huei Tseng

Published in: Journal of gastroenterology and hepatology (2024)

A notably high prevalence (83.2%) of FED was observed among patients experiencing PPI-unresponsive reflux symptoms. Patients with FED had a higher level of psychological distress and diminished sleep quality, both of which were associated with reflux symptom severity.

Keyphrases

sleep quality
depressive symptoms
physical activity
risk factors
protein protein
small molecule
electron transfer