Molecular Profiles of Advanced Urological Cancers in the PERMED-01 Precision Medicine Clinical Trial.
Emilien BillonGwenaelle GravisArnaud GuilleNadine CarbucciaJose AdelaideSéverine GarnierPascal FinettiEmilie DenicolaïPatrick SfumatoSerge BrunelleJeanne Thomassin-PianaGéraldine PignotJochen WalzChristian ChabanonJihane PakradouniRenaud SabatierCécile VicierCornel PopoviciEmilie MamessierAnthony GoncalvesDaniel BirnbaumMax ChaffanetFrançois BertucciPublished in: Cancers (2022)
the profiling of a newly biopsied tumor sample identified AGA in 59% of patients with AUC, led to "matched therapy" in 19%, and provided clinical benefit in 8%.