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Exploration of quantitative site-specific serum O-glycoproteomics with isobaric labeling for the discovery of putative O-glycoprotein biomarkers.

Zihan ZhangHua XuZhixin Tian
Published in: Proteomics. Clinical applications (2022)
Isobaric-labeling site-specific quantitative O-glycoproteomics is currently a state-of-the-art instrumental platform for discovery of putative seral cancer biomarkers. Differential seral O-glycosylation was observed in the IgG1 and IgG3.
Keyphrases
  • high throughput
  • small molecule
  • high resolution
  • papillary thyroid
  • squamous cell
  • squamous cell carcinoma
  • childhood cancer