Changes in Tophus Composition During Urate-Lowering Therapy: A Dual-Energy Computed Tomography Study.

Leanne ChenGregory D GambleAnne HorneJill DrakeAnthony J DoyleTill Uhlig Lisa K Stamp Nicola Dalbeth

Published in: Arthritis care & research (2023)

The composition of the tophus is dynamic and changes during urate-lowering therapy for gout management. The soft tissue component of the tophus is slower to respond and may persist without measurable MSU crystal deposition.

Keyphrases

computed tomography
dual energy
soft tissue
image quality
positron emission tomography
magnetic resonance imaging
contrast enhanced
uric acid
magnetic resonance
mesenchymal stem cells
cell therapy
smoking cessation