Placental and Umbilical Cord Blood Oxidative Stress Level and Telomere Homeostasis in Early Onset Severe Preeclampsia.

Emre BaşerNihal InandikliogluDemet Aydogan Kirmizi Fedi ErcanAyşen CaniklioğluMustafa KaraTaylan OnatEthem Serdar Yalvac

Published in: Zeitschrift fur Geburtshilfe und Neonatologie (2022)

This study found that oxidative stress is an independent risk factor in the development of PE and shortens TL in both placental and umbilical cord blood. Future research on telomere homeostasis may offer a new perspective for the treatment of PE.

Keyphrases

umbilical cord
early onset
mesenchymal stem cells
oxidative stress
late onset
dna damage
risk factors
ischemia reperfusion injury
diabetic rats
bone marrow
induced apoptosis
pregnant women
combination therapy
signaling pathway
endoplasmic reticulum stress