Evidence of Residual Ongoing Viral Replication in Chronic Hepatitis B Patients Successfully Treated with Nucleos(t)ide Analogues.

Tong YuMiaoqu ZhangHanyue ZhangJianming ZhengChuan ShenNing JiangLei ZouJing WangYiqi YuQiran ZhangShuili YuYanfang HuangYuxian HuangJi-Ming ZhangChao QiuWenhong ZhangZhefeng Meng

Published in: The Journal of infectious diseases (2022)

We therefore conclude that even after prolonged treatment, a small proportion of the cccDNA reservoir is constantly replenished by continued low-level HBV replication, whereas the greatest amount of cccDNA reservoir persists over time.

Keyphrases

hepatitis b virus
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
molecular docking
water quality