Metabolic landscape of head and neck squamous cell carcinoma informs a novel kynurenine/Siglec-15 axis in immune escape.

Xin-Yu ZhangJian-Bo ShiShu-Fang JinRui-Jie WangMing-Yu LiZhi-Yuan ZhangXi YangHai-Long Ma

Published in: Cancer communications (London, England) (2024)

The findings describe the metabolic landscape of HNSCC comprehensively and reveal that the Kyn/Siglec-15 axis may be a novel potential immunometabolism mechanism, providing a promising therapeutic strategy for cancers.

Keyphrases

single cell
genome wide
gene expression