Purple Carrot Extract Exhibits a Neuroprotective Profile in th e Nigrostriatal Pathway in the Reserpine-induced Model of Parkinson 's Disease.
Ana Claudia Custódio-SilvaJose Ivo Araújo Beserra-FilhoBeatriz Soares-SilvaAmanda Maria-MacêdoSuellen Silva-MartinsSara Pereira SilvaJosé Ronaldo SantosRegina Helena SilvaDaniel Araki RibeiroAlessandra Mussi RibeiroPublished in: Central nervous system agents in medicinal chemistry (2024)
CAR extract is effective to attenuate motor symptoms in rats associated with increased TH+ levels in the Ventral Tegmental Area (VTA) and SNpc, indicating the potential nutraceutical benefits of CAR extract in a progressive parkinsonism model induced by RES.