Cerebral Multishell Diffusion Imaging Parameters are Associated with Blood Biomarkers of Disease Severity in HIV Infection.
Francesco GaraciEliseo PicchiFrancesca Di GiulianoSimona LanzafameSilvia MinosseGuglielmo ManentiChiara Adriana PistoleseLoredana SarmatiElisabetta TetiMassimo AndreoniRoberto FlorisNicola ToschiPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2019)
In HIV-positive subjects, associations between biochemical and diffusion-MRI variables are found along the association fibers, which connect brain areas involved in memory formation, providing a possible interpretation for the neurobiological substrate underlying cognitive disturbances in HIV.
Keyphrases
- hiv positive
- antiretroviral therapy
- hiv infected
- men who have sex with men
- human immunodeficiency virus
- south africa
- hiv aids
- high resolution
- hiv testing
- cerebral ischemia
- magnetic resonance imaging
- subarachnoid hemorrhage
- contrast enhanced
- white matter
- working memory
- mass spectrometry
- hepatitis c virus
- fluorescence imaging