Insula and amygdala resting-state functional connectivity differentiate bipolar from unipolar depression.

E AmbrosiD B ArciniegasA MadanK N CurtisM A PatriquinR E JorgeG SpallettaJ C FowlerB C FruehRamiro Salas

Published in: Acta psychiatrica Scandinavica (2017)

rsFC of amygdala and insula distinguished between depressed BD and MDD. The observed differences suggest the possibility of differential pathophysiological mechanisms of emotional dysfunction in bipolar and unipolar depression.

Keyphrases

functional connectivity
resting state
bipolar disorder
depressive symptoms
sleep quality
major depressive disorder
oxidative stress
physical activity
stress induced
prefrontal cortex