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Improvement of Workflows and Assay Reproducibility by The Introduction of "Assay-Ready" Culturing of MDCK Cells for Transport Studies.

Patricia MuschongLiang JinJan SchejbalMario MezlerManuel Weinheimer
Published in: Pharmaceutical research (2023)
Assay-ready methodology for handling MDCK_ZFN cells allows more flexibility in assay planning and reduces performance fluctuations in assays caused by cell aging. Therefore, the assay-ready principle has proven superior over conventional cultivation for MDCK_ZFN cells and is considered as a key technology to optimize processes with other cellular systems.
Keyphrases
  • induced apoptosis
  • high throughput
  • cell cycle arrest
  • endoplasmic reticulum stress
  • stem cells
  • cell therapy
  • oxidative stress