A comprehensive analysis of tumor-stromal collagen in relation to pathological, molecular, and immune characteristics and patient survival in pancreatic ductal adenocarcinoma.
Shigeto AshinaAtsuhiro MasudaKohei YamakawaTsuyoshi HamadaMasahiro TsujimaeTakeshi TanakaHirochika ToyamaKeitaro SofueHideyuki ShiomiArata SakaiTakashi KobayashiShohei AbeMasanori GondaShigeto MasudaNoriko InomataHisahiro UemuraShinya KohashiKae NagaoYoshiyuki HaradaMika MikiNoriko JuriYosuke IrieMaki KanzawaTomoo ItohJun InoueToshio ImaiTakumi FukumotoYuzo KodamaPublished in: Journal of gastroenterology (2023)
Tumor-stromal collagen deposition may play a crucial role in modulating tumor-immune microenvironment and determining response to adjuvant chemotherapy and patient survival outcomes.