How limited molecular testing can also offer diagnostic and prognostic evaluation of thyroid nodules processed with liquid-based cytology: Role of TERT promoter and BRAF V600E mutation analysis.
Marco Dell'AquilaVincenzo FiorentinoMaurizio MartiniSara CapodimontiTonia CenciCelestino Pio LombardiMarco RaffaelliAlfredo PontecorviGuido FaddaLiron PantanowitzLuigi Maria LaroccaEsther Diana RossiPublished in: Cancer cytopathology (2021)
BRAF V600E and TERT analysis can be performed on LBC. TERT mutations are rarely identified in well differentiated thyroid carcinoma but are associated with higher stage. Although a larger molecular panel may offer more information, analyzing these few point mutations is still likely to be useful for managing potentially more aggressive thyroid carcinomas.