Renoprotective Effect of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, in Streptozotocin-Induced Type 1 Diabetic Mice.

Gwon Soo JungJae Han JeonMi Sun ChoeSung Woo KimIn Kyu LeeMi Kyung Kim Keun Gyu Park

Published in: Diabetes & metabolism journal (2016)

Our data demonstrate that gemigliptin has renoprotective effects on DKD, regardless of its glucose-lowering effect, suggesting that it could be used to prevent DKD, including in patients with type 1 diabetes.

Keyphrases

diabetic rats
diabetic nephropathy
oxidative stress
high glucose
high fat diet
electronic health record
big data
blood glucose
drug induced
type diabetes
endothelial cells
machine learning
skeletal muscle
deep learning