PTEN allelic loss is an important mechanism in the late stage of development of oral leucoplakia into oral squamous cell carcinoma.
Ligia A N MiyaharaFlávia S C PontesRommel M R BurbanoNicolau Conte NetoDouglas M GuimarãesFlávia Sirotheau Correa PontesHelder Antonio Rebelo PontesPublished in: Histopathology (2017)
The results of this work suggest that PTEN allelic loss is an important mechanism in the late stage of the development of oral potentially malignant lesions into oral cancer.