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Acute Tubulointerstitial Nephritis in a Patient on Anti-Programmed Death-Ligand 1 Triggered by COVID-19: A Case Report.

Dimitry BuyanskyCatherine FallahaFrançois GougeonMarie-Noëlle PépinJean-François CailhierWilliam Beaubien-Souligny
Published in: Canadian journal of kidney health and disease (2021)
We hypothesize that the viral infection along with checkpoint inhibitor use has created a proinflammatory environment which led to a loss of self-tolerance to renal parenchyma. Viruses may play a more important role in the pathogenesis of autoimmunity in this patient population than was previously thought.
Keyphrases
  • case report
  • coronavirus disease
  • sars cov
  • liver failure
  • cell cycle
  • respiratory failure
  • oxidative stress
  • diabetic nephropathy