PD-L1 as a Prognostic Factor in Early-Stage Colon Carcinoma within the Immunohistochemical Molecular Subtype Classification.

Pablo AzcueIgnacio J EncíoDavid Guerrero SetasJavier Suarez AlechaArkaitz GalbeteMaría MercadoRuth VeraMaria Luisa Gomez-Dorronsoro

Published in: Cancers (2021)

Our study suggests that PD-L1 expression is an independent prognostic factor in patients with stage II/III colon cancer. Additionally, it successfully differentiates patients with better prognosis in the CMS2/CMS3 group and may prove significant for the clinical relevance of the CMS classification.

Keyphrases

prognostic factors
early stage
machine learning
deep learning
squamous cell carcinoma
neoadjuvant chemotherapy
sentinel lymph node