Functionalized Mesoporous Silica Nanoparticles for Drug-Delivery to Multidrug-Resistant Cancer Cells.
Nóra IgazPéter BéltekyDávid KovácsCsaba PappAndrea RónaváriDiána SzabóAttila GácserZoltán KónyaMónika KiricsiPublished in: International journal of nanomedicine (2022)
The efficient delivery of Rho123 and MMC to multidrug-resistant cells via MSNs, the amplified and presumably prolonged intracellular drug concentration, and the consequently enhanced cytotoxic effects envision the enormous potential of MSNs to defeat multidrug-resistant cancer.
Keyphrases
- multidrug resistant
- drug resistant
- gram negative
- acinetobacter baumannii
- drug delivery
- klebsiella pneumoniae
- induced apoptosis
- papillary thyroid
- cell cycle arrest
- squamous cell
- quantum dots
- endoplasmic reticulum stress
- squamous cell carcinoma
- oxidative stress
- emergency department
- escherichia coli
- human health
- molecularly imprinted
- adverse drug
- drug release
- liquid chromatography
- anti inflammatory