Surgery and Proton Radiation Therapy for Pediatric Base of Skull Chordomas: Long-term Clinical Outcomes for 204 patients.
Myrsini Ioakeim-IoannidouAndrzej NiemierkoDaniel W KimAthena TejadaTobias UrellShannon LeahyJudy AdamsBarbara FullertonG Petur NielsenYin Pun HungAngela R ShihManuel PatinoKaren BuchSandra RinconHilary KellyMary Beth CunnaneMaria ToliaBrigitte C WidemannMary F WedekindLiny JohnDavid EbbJohn H ShinGregory CoteWilliam CurryShannon M MacDonaldPublished in: Neuro-oncology (2023)
This is the largest cohort of BOS chordomas in the literature, pediatric and/or adult. High-dose PRT following surgical resection is effective with low rates of late toxicity.