Diethylnitrosamine (DENA) recapitulates formation of hepatic angiosarcoma in pigs.
Sonja M KesslerBettina LeberJessica HoppstädterNicole Golob-SchwarzlEva M HoferChristina S SchultheissHans-Jörg MischingerBernadette Liegl-AtzwangerCarolin LacknerPhilipp StieglerJohannes HaybaeckPublished in: PloS one (2019)
In this preliminary study treatment of sus scrofa with weekly injections of 15 mg/kg DENA results in a new model for primary hepatic angiosarcoma. This model may help to shed light on the pathomechanisms of primary hepatic angiosarcoma and might therefore open new treatment options.
Keyphrases