Mangosteen Hinders Gamma Radiation-Mediated Oxidative Stress and Liver Injury by Down-Regulating TNF-α/NF-κB and Pro-Fibrotic Factor TGF-β1 Inducing Inflammatory Signaling.
Asmaa A HassanEnas Mahmoud MoustafaIman Hesham El-KhashabSomaya Z MansourPublished in: Dose-response : a publication of International Hormesis Society (2021)
We concluded that MGS could ameliorate via minimizing significantly the amount of oxidative damage, inflammations disturbances and pro-apoptotic alternations induced by IR. MGS may be a promising supplement with protective effects from irradiation-induced injury such as TNF-α/NF-κB/TGF-β1 management.
Keyphrases
- oxidative stress
- diabetic rats
- anti inflammatory
- transforming growth factor
- rheumatoid arthritis
- signaling pathway
- lps induced
- cell death
- induced apoptosis
- pi k akt
- ischemia reperfusion injury
- dna damage
- nuclear factor
- high glucose
- systemic sclerosis
- radiation induced
- epithelial mesenchymal transition
- idiopathic pulmonary fibrosis
- inflammatory response
- drug induced
- radiation therapy
- heat shock
- toll like receptor