Login / Signup

Increase in oxidative stress levels following welding fume inhalation: a controlled human exposure study.

Halshka GraczykNastassja LewinskiJiayuan ZhaoJean-Jacques SauvainGuillaume SuarezPascal WildBrigitta DanuserMichael Riediker
Published in: Particle and fibre toxicology (2016)
A 60-min exposure to TIG welding fume in a controlled, well-ventilated setting induced acute oxidative stress at 3 h post exposure in healthy, non-smoking apprentice welders not chronically exposed to welding fumes. As mass concentration of TIG welding fume particles is very low when compared to other types of welding, it is recommended that additional exposure metrics such as PNC are considered for occupational risk assessments. Our findings highlight the importance of increasing awareness of TIG welding fume toxicity, especially given the realities of welding workplaces that may lack ventilation; and beliefs among interviewed welders that TIG represents a cleaner and safer welding process.
Keyphrases
  • oxidative stress
  • dna damage
  • endothelial cells
  • signaling pathway
  • heat shock protein
  • heat shock
  • heat stress