Anti-platelet antibody immunoassays in childhood immune thrombocytopenia: a systematic review.
David E SchmidtAnke J LakerveldKatja M J Heitink-PolléMarrie C A BruinGestur VidarssonLeendert PorcelijnMasja de HaasPublished in: Vox sanguinis (2020)
The diagnostic evaluation of IgG and IgM anti-platelet antibodies may be useful as a rule-in test for ITP. In children with insufficient platelets for a direct test, indirect tests may be performed instead. A negative test does not rule out the diagnosis of ITP. Future studies should evaluate the value of anti-platelet antibody tests in thrombocytopenic children with suspected ITP.