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Synophtalmia on a newborn.

Laetitia Bihamba BiraFranck Katembo SikakulyaMupenzi MumbereJeff Mathe
Published in: SAGE open medical case reports (2022)
Synophtalmia or cyclopia is a rare presentation of alobar holoprosencephaly. Cases which have been reported are stillborn or dead in post-delivery period. We are presenting a 3000-g live full-term newborn girl delivered by caesarean section with a well-marked cyclopia, but who died 30 min post-delivery. The case did not present with other abnormalities. The literature showed that genetic disorders are associated with cyclopia. A prenatal anomaly scan can help in the early detection of the condition and timely termination of the pregnancy can be conducted.
Keyphrases
  • systematic review
  • case report
  • computed tomography
  • pregnant women
  • preterm birth
  • genome wide
  • gene expression
  • pregnancy outcomes
  • copy number
  • dna methylation