Salvage Therapy in Early Relapse of T-Lymphoblastic Leukemia/Lymphoma Using Daratumumab/Nelarabine Combination: Two Consecutive Cases.
Ingolf MølleIrma PetruskeviciusPeter KamperFrancesco d'AmorePublished in: Case reports in hematology (2022)
Treatment of early relapses of T lymphoblastic leukemia/lymphoma is often unsuccessful. We tested an experimental regimen containing daratumumab and nelarabine in two young patients with early relapses of T lymphoblastic lymphoma and T-ALL, respectively. Both patients achieved a deep complete remission. Combining daratumumab with chemotherapy may have a role in relapsing T lymphoblastic leukemia/lymphoma.
Keyphrases
- diffuse large b cell lymphoma
- acute myeloid leukemia
- multiple myeloma
- bone marrow
- multiple sclerosis
- end stage renal disease
- ejection fraction
- newly diagnosed
- disease activity
- prognostic factors
- squamous cell carcinoma
- radiation therapy
- rheumatoid arthritis
- mesenchymal stem cells
- patient reported outcomes
- patient reported
- free survival
- smoking cessation