Two-site evaluation of a new workflow for the detection of malignant cells on the Sysmex XN-1000 body fluid analyzer.
Julien FavresseLidvine BolandMarie SchellenCaroline FervailleFabien WuestenberghsAlessandra CamboniBernard ChatelainFrançois MullierJean-Philippe DefourHugues JacqminPublished in: International journal of laboratory hematology (2020)
Combining clinical information and HF-BF reached 100% sensitivity for malignant cell detection in body fluid analysis. Lack of robustness of the optimal HF-BF cutoff deserves the use of local cutoffs. Rapid automated results reporting from the XN-1000 BF mode are also feasible in clinical practice. Prospective evaluation of the workflow is needed before its implementation in clinical practice.
Keyphrases
- clinical practice
- loop mediated isothermal amplification
- induced apoptosis
- real time pcr
- primary care
- healthcare
- electronic health record
- cell cycle arrest
- single cell
- cell therapy
- sensitive detection
- high throughput
- health information
- adverse drug
- stem cells
- oxidative stress
- signaling pathway
- atrial fibrillation
- social media
- cell proliferation
- quantum dots