Urbanization in China is associated with pronounced perturbation of plasma metabolites.
Yiqing WangWei ShaHuijun WangAnnie Green HowardMatthew C B TsilimigrasZhi-Hong WangChang SuZhihong WangBing ZhangAnthony A FodorPenny Gordon-LarsenPublished in: Metabolomics : Official journal of the Metabolomic Society (2020)
We detected profound differences in host metabolites by urbanization status. Urban residents were characterized by metabolites signaling caffeine metabolism and toxic pollutants and metabolites on known pathways to cardiometabolic disease risks, compared to their rural counterparts. Our findings highlight the importance of considering urbanization in metabolomics analysis.