Variability of clinically measured lung clearance index in children with cystic fibrosis.

Bettina S FrauchigerKathryn A RamseyJakob UsemannElisabeth KieningerCarmen CasaultaDaniel SirtesSophie YammineBen SpycherAlexander MöllerPhilipp Latzin

Published in: Pediatric pulmonology (2022)

We report the variability of LCI in children and adolescents with CF during routine clinical surveillance. According to our data, a change in LCI beyond 19% may be considered physiologically relevant. These findings will help guide clinical decisions according to LCI changes.

Keyphrases

cystic fibrosis
young adults
public health
clinical practice
machine learning
data analysis