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Enantioselective Total Synthesis of Cannabinoids-A Route for Analogue Development.

Zachary P ShultzGrant A LawrenceJeffrey M JacobsonEmmanuel J CruzJames W Leahy
Published in: Organic letters (2018)
A practical synthetic approach to Δ9-tetrahydrocannabinol (1) and cannabidiol (2) that provides scalable access to these natural products and should enable the generation of novel synthetic analogues is reported.
Keyphrases
  • molecular docking
  • structure activity relationship