Non-visualization of choroid plexus of fourth ventricle as first-trimester predictor of posterior fossa anomalies and chromosomal defects.

P Martinez-TenT IllescasB AdiegoM EstevezC BermejoA E WongWaldo Sepulveda

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2018)

Non-visualization of the CP-4V in the first trimester appears to be a strong marker of posterior fossa anomalies and chromosomal defects. Qualitative evaluation of this anatomic structure is simple, feasible and reproducible, and its routine assessment during the first-trimester scan may facilitate the early detection of CNS anomalies and associated fetal aneuploidy. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

copy number
computed tomography
systematic review
blood brain barrier
pulmonary artery
mitral valve
clinical practice
ultrasound guided
magnetic resonance imaging
magnetic resonance
gene expression
dna methylation
congenital heart disease