In severe obesity, subcutaneous adipose tissue cell-derived cytokines are early markers of impaired glucose tolerance and are modulated by quercetin.

Vittoria D'EspositoMaria Rosaria AmbrosioDomenico LiguoroGiuseppe PerruoloManuela LecceSerena CabaroMarianna AprileAda MarinoVincenzo PilonePietro ForestieriClaudia MieleDario BruzzeseDaniela TerraccianoFrancesco BeguinotPietro Formisano

Published in: International journal of obesity (2005) (2021)

In severe obesity, enhanced SAT-derived inflammatory phenotype is an early step in the progression toward T2D and maybe, at least in part, attenuated by quercetin.

Keyphrases

insulin resistance
adipose tissue
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
early onset
high fat diet
skeletal muscle
oxidative stress
drug induced
body mass index
physical activity