A PHLDB1 variant associated with the nonfunctional pituitary adenoma.

Lyoung Hyo KimJeong-Hyun KimSuhg NamgoongHyun Sub CheongSeon-Jin YoonEui Hyun KimSe Hoon KimSun Ho KimJong Hee ChangHyoung Doo Shin

Published in: Journal of neuro-oncology (2019)

Our findings suggest that genetic variation of PHLDB1 may be associated with the risk of NFPA. This is the first report of an association between PHLDB1 variants and NFPA. Further research is needed to confirm the impact of this SNP on NFPA susceptibility.

Keyphrases

genome wide
copy number
neuroendocrine tumors
gene expression
dna methylation