Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer.

Sonali BhattacharjeeSaikat Nandi

Published in: Clinical and translational medicine (2016)

The DNA repair field is a vibrant one, and the stage is ripe for scrutinizing the potential treatment efficacy and future clinical applications of the pharmacological inhibitors of HR enzymes as mono- or combinatorial therapy regimes.

Keyphrases

dna repair
dna damage
dna damage response
papillary thyroid
squamous cell
current status
copy number
stem cells
young adults
gene expression
lymph node metastasis
replacement therapy
childhood cancer
mesenchymal stem cells
climate change
cell therapy