The Impact of Morbid Obesity on the Health Outcomes of Hospital Inpatients: An Observational Study.
Kellie FuscoCampbell Henry ThompsonRichard John WoodmanChris HorwoodPaul HakendorfYogesh SharmaPublished in: Journal of clinical medicine (2021)
Morbid obesity poses a significant burden on the health-care system. This study determined whether morbid obesity leads to worse health-outcomes in hospitalised patients. This retrospective-study examined nutritional data of all inpatients aged 18-79 years, with a body-mass-index (BMI) ≥ 18.5 kg/m2 admitted over a period of 4 years at two major hospitals in Australia. Patients were divided into 3 groups for comparison: normal/overweight (BMI 18.5-29.9 kg/m2), obese (BMI 30-39.9 kg/m2) and morbidly-obese (BMI ≥ 40 kg/m2). Outcome measures included length-of-hospital-stay (LOS), in-hospital mortality, and 30-day readmissions. Multilevel-mixed-effects regression was used to compare clinical outcomes between the groups after adjustment for potential confounders. Of 16,579 patients, 1004 (6.1%) were classified as morbidly-obese. Morbidly-obese patients had a significantly longer median (IQR) LOS than normal/overweight patients (5 (2, 12) vs. 5 (2, 11) days, p value = 0.012) and obese-patients (5 (2, 12) vs. 5 (2, 10) days, p value = 0.036). After adjusted-analysis, morbidly-obese patients had a higher incidence of a longer LOS than normal/overweight patients (IRR 1.04; 95% CI 1.02-1.07; p value < 0.001) and obese-patients (IRR 1.13; 95% CI 1.11-1.16; p value < 0.001). Other clinical outcomes were similar between the different groups. Morbid obesity leads to a longer LOS in hospitalised patients but does not adversely affect other clinical outcomes.
Keyphrases
- obese patients
- bariatric surgery
- weight loss
- end stage renal disease
- body mass index
- ejection fraction
- gastric bypass
- metabolic syndrome
- roux en y gastric bypass
- newly diagnosed
- type diabetes
- chronic kidney disease
- weight gain
- healthcare
- prognostic factors
- peritoneal dialysis
- emergency department
- adipose tissue
- physical activity
- patient reported outcomes
- climate change
- risk factors
- big data
- machine learning
- artificial intelligence
- high fat diet induced