Acylcarnitines and Genetic Variation in Fat Oxidation Genes in HIV-infected, Antiretroviral-treated Children With and Without Myopathy.

Brian KirmseCharlotte HobbsLisa AaronGrace MontepiedraMarshall SummarPaige L WilliamsCaitlin J SmithRussell Van DykeChunli YuKelli K RyckmanWilliam Borkowskynull null

Published in: The Pediatric infectious disease journal (2022)

FAO appears to be altered in HIV-infected children with and without myopathy, but abnormal FAO does not fully explain myopathy in ARV-exposed children. Further study of SLC22A5 variation in ARV-exposed people is warranted carnitine transporter dysfunction-related cardiomyopathy may be treatable.

Keyphrases

hiv infected
antiretroviral therapy
young adults
late onset
human immunodeficiency virus
heart failure
adipose tissue
hiv positive
hiv aids
oxidative stress
gene expression
hydrogen peroxide
nitric oxide
atrial fibrillation
south africa
men who have sex with men