Liposomal bupivacaine versus conventional anesthetic or placebo for hemorrhoidectomy: a systematic review and meta-analysis.

P Solis-PazminoL FigueroaK LaO TermeieK OkaM SchleicherJ CohenM BarnajianYosef Nasseri

Published in: Techniques in coloproctology (2024)

Comparing LB to conventional anesthetic/placebo anesthetic for hemorrhoidectomy, we found a statistically significant reduction in pain through 72 h, decreased opioid requirements, and delayed time to first opioid use. Moreover, the conventional anesthetic/placebo group reported more pain in bowel movement than LB groups.

Keyphrases

pain management
chronic pain
double blind
neuropathic pain
phase iii
postoperative pain
placebo controlled
spinal cord injury