Epidemiology of cerebral microbleeds and risk of adverse outcomes in atrial fibrillation: a systematic review and meta-analysis.
Bernadette CoricaGiulio Francesco RomitiValeria RaparelliRoberto CangemiStefania BasiliMarco ProiettiPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2022)
Cerebral microbleeds are common in patients with AF, found in almost one out of four subjects. Cerebral microbleeds were associated with both haemorrhagic and thromboembolic events in AF patients. Moreover, the risk of ICH increased consistently with the burden of CMBs. Cerebral microbleeds may represent an important overlooked risk factor for both ICH and IS in adults with AF.
Keyphrases
- atrial fibrillation
- subarachnoid hemorrhage
- end stage renal disease
- oral anticoagulants
- cerebral ischemia
- catheter ablation
- left atrial appendage
- newly diagnosed
- brain injury
- ejection fraction
- chronic kidney disease
- direct oral anticoagulants
- prognostic factors
- percutaneous coronary intervention
- cerebral blood flow
- left ventricular
- coronary artery disease
- acute coronary syndrome