Anti-tumour effect of neo-antigen-reactive T cells induced by RNA mutanome vaccine in mouse lung cancer.

Jiaxing SunJing ZhangHaiyan HuHuan QinXiming LiaoFeilong WangWei ZhangQi YinXiaoping SuYanan HeWenfeng LiKun WangQiang Li

Published in: Journal of cancer research and clinical oncology (2021)

NRT cells induced by RNA mutanome vaccine exert a significant anti-tumour effect in mouse lung cancer, and adoptive NRT cell therapy might be considered a feasible, effective therapeutic approach for lung cancer.

Keyphrases

cell therapy
stem cells
mesenchymal stem cells
induced apoptosis
cell cycle arrest
cell death
signaling pathway
bone marrow
cell proliferation