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Canakinumab as Adjuvant Therapy in Patients With Completely Resected Non-Small-Cell Lung Cancer: Results From the CANOPY-A Double-Blind, Randomized Clinical Trial.

Edward B GaronShun LuYasushi GotoPedro De MarchiLuis G Paz-AresDavid R SpigelMichael ThomasJames Chih-Hsin YangAndrea ArdizzoniFabrice BarlesiSergey V OrlovHiroshige YoshiokaGiannis MountziosSadhvi KhannaClaudia BossenMariana CarbiniSabine TurriAndrea MyersByoung Chul Cho
Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
CANOPY-A did not show a DFS benefit of adding canakinumab after surgery and adjuvant cisplatin-based chemotherapy in patients with resected, stage II-III NSCLC. No new safety signals were identified with canakinumab.
Keyphrases
  • lymph node
  • small cell lung cancer
  • early stage
  • prognostic factors
  • locally advanced
  • advanced non small cell lung cancer
  • squamous cell carcinoma
  • clinical trial
  • radiation therapy
  • rectal cancer
  • chemotherapy induced