Associations between child filaggrin mutations and maternal diet with the development of allergic diseases in children.
Carina VenterMicheala P PalumboKatherine Ann SauderDeborah H GlueckCorina M BersetIvana YangElizabeth J DavidsonHelen Annaruth BroughJohn W HollowayDavid M FleischerMiriam Ben-AbdallahDana M DabeleaPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2022)
Children with FLG mutation had similar risk of atopic dermatitis, asthma, and wheeze as children without an FLG mutation whose mothers did not eat an allergy preventive diet during pregnancy. Child FLG mutation did not modify the effect of maternal diet. The results suggest that maternal diet in pregnancy, a modifiable risk factor, could be a target for preventive interventions.