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MicroRNA-Based Markers of Oral Tongue Squamous Cell Carcinoma and Buccal Squamous Cell Carcinoma: A Systems Biology Approach.

Setareh ShojaeiPouya MenbariShokoofeh JamshidiAmir Taherkhani
Published in: Biochemistry research international (2023)
The present study suggests that has-miR-136 and has-miR-377 are underexpressed in OTSCC and BSCC than in normal oral mucosa. Moreover, EIF2S1, CAV1, RAN, ANXA5, CYCS, CFL1, MYC, HSP90AA1, PKM, HSPA5, NTRK2, HNRNPH1, DDX17, and WDR82 demonstrated prognostic markers in HNSCC. These findings may benefit the prognosis and management of individuals with OTSCC/BSCC. However, additional experimental verification is required.
Keyphrases
  • squamous cell carcinoma
  • cell proliferation
  • long non coding rna
  • heat shock protein
  • long noncoding rna
  • locally advanced
  • lymph node metastasis
  • transcription factor
  • heat shock
  • oxidative stress