GO/Cu Nanosheet-Integrated Hydrogel Platform as a Bioactive and Biocompatible Scaffold for Enhanced Calvarial Bone Regeneration.
Ying YangBixia ZhouMin LiYishuai SunXulei JiangXinxin ZhouChengjun HuDou ZhangHang LuoWuyuan TanXinghua YangShaorong LeiPublished in: International journal of nanomedicine (2024)
Taken together, this BTE-based bone repair strategy provides a promising and feasible method for constructing multifunctional GO/Cu nanocomposite-incorporated biohybrid hydrogel scaffolds with facilitated osteogenesis, angiogenesis and immunoregulation in one system, with the optimization of material properties and biosafety, it thereby demonstrates great application potential for correcting craniofacial bone defects in future clinical scenarios.
Keyphrases
- bone regeneration
- tissue engineering
- drug delivery
- wound healing
- aqueous solution
- metal organic framework
- climate change
- endothelial cells
- hyaluronic acid
- cancer therapy
- high throughput
- ionic liquid
- current status
- reduced graphene oxide
- high resolution
- body composition
- bone mineral density
- postmenopausal women
- bone loss