Epigenetic regulatory axis MIR22-TET3-MTRNR2L2 represses fibroblast-like synoviocyte-mediated inflammation in Rheumatoid Arthritis.

Yilong FangWei HuangXiangling ZhuXinming WangXuming WuHuihui WangWenming HongShangxue YanLingling ZhangYujie DengWei Wei Jiajie TuChen Zhu

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2024)

The key role of the MIR22-TET3-MTRNR2L2 pathway in RA-FLS provided an experimental basis for further studies into the pathogenesis and related targets of RA from the perspective of FLS.

Keyphrases

rheumatoid arthritis
cell proliferation
long non coding rna
disease activity
long noncoding rna
ankylosing spondylitis
interstitial lung disease
oxidative stress
dna methylation
gene expression
transcription factor
systemic sclerosis