Impact of natural menopause on multiple sclerosis: a multicentre study.
Damiano BaronciniPietro Osvaldo AnnovazziNicola De RossiGiulia MallucciValentina Torri ClericiSimone ToniettiVittorio ManteroMaria Teresa FerròMaria Josè MessinaValeria BarcellaLoredana La MantiaMarco RonzoniCaterina BarrilàRaffaella ClericiEmanuela Laura SusaniMaria Letizia FuscoLuca ChiveriLucia AbateOttavia FerraroRuggero CapraElena ColomboPaolo ConfalonieriMauro ZaffaroniPublished in: Journal of neurology, neurosurgery, and psychiatry (2019)
Natural menopause seems to be a turning point to a more progressive phase of MS. Relapse rate is also reduced after menopause, but this effect could be driven most by ageing and shifting to progressive phase in patients with long-lasting disease. Cigarette smoking could speed up disability progression after menopause.