Application of multilevel linear spline models for analysis of growth trajectories in a cohort with repeat antenatal and postnatal measures of growth: a prospective cohort study.

Linda Marie O'KeeffeCara A YelvertonHelena C Bartels Kate N O'NeillCiara McDonnellFionnuala M McAuliffe

Published in: BMJ open (2023)

We demonstrate the application of multilevel linear spline models for examining growth trajectories when both antenatal and postnatal measures of growth are available. The approach may be useful for cohort studies or randomised control trials with repeat prospective assessments of growth.

Keyphrases

pregnant women
clinical trial
preterm infants
preterm birth
double blind
open label