Leptomeningeal disease and brain control after postoperative stereotactic radiosurgery with or without immunotherapy for resected brain metastases.

Giuseppe MinnitiGaetano LanzettaLuca CaponeMartina GiraffaIvana RussoFrancesco CiconeAlessandro BozzaoFilippo AlongiLuca NicosiaGioia FineschiLuca MarchettiTommaso TufoFederico BianciardiVincenzo EspositoPierCarlo GentileSergio Paolini

Published in: Journal for immunotherapy of cancer (2022)

Postoperative fSRS in combination with immunotherapy decreases the incidence of LMD and DBF in patients with resected BM from NSCLC and melanoma as compared with fSRS alone, reducing the rate of neurological death and prolonging survival.

Keyphrases

brain metastases
small cell lung cancer
patients undergoing
lymph node
cerebral ischemia
resting state
white matter
functional connectivity
advanced non small cell lung cancer
blood brain barrier